SCHEMBL26011

SCHEMBL26011

[CH]1C=Cc2c1ccc1ccccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP2A6 P11509 5/20 0.46
HSD17B10 Q99714 4/20 0.46
TSHR P16473 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
HPRT1 P00492 1/20 0.42
CES1 P23141 2/20 0.40
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
P2RX4 Q99571 1/20 0.36
CYP1A2 P05177 4/20 0.35
PTPN22 Q9Y2R2 1/20 0.35
PAX8 Q06710 1/20 0.35
HPGD P15428 2/20 0.34
THRB P10828 1/20 0.34
CYP3A4 P08684 1/20 0.33
KEAP1 Q14145 1/20 0.33
F12 P00748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6545899 0.79 ALDH1A1 (0.52) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL28031408 0.76 HPRT1 (0.47) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL6647826 0.75 POLB (0.36) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL27504826 0.75 POLB (0.36) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL7037991 0.74 HSD17B10 (0.41) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL401275 0.72 ALDH1A1 (0.55) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL20972408 0.71 CYP2A6 (0.33) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL11250908 0.71 ALDH1A1 (0.42) ALDH1A1CYP2A6HSD17B10TSHRTDP1
SCHEMBL3783382 0.69 CES1 (0.44) ALDH1A1CYP2A6HSD17B10TSHRTDP1
Phenanthrene SCHEMBL30932938 0.66 CYP2A6 (1.00) ALDH1A1CYP2A6HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US claimed
US-20230212330-A1 Metallocene Catalysts for Producing Vinyl-Terminated Polyalphaolefins and Methods Associated Therewith EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-07-06 US claimed
US-20210402384-A1 Hexahydrocyclopenta[e]-as-indacen-1-yl and Octahydrobenzo[e]-as-indacen-1-yl based Catalyst Complexes and Process for Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2021-12-30 US claimed
WO-2021257264-A1 METALLOCENE CATALYSTS FOR PRODUCING VINYL-TERMINATED POLYALPHAOLEFINS AND METHODS ASSOCIATED THEREWITH EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-23 WO claimed
WO-2021112489-A1 METHOD FOR PRODUCING OLEFIN-BASED POLYMER 한화솔루션 주식회사 2021-06-10 WO claimed
WO-2020116842-A1 METHOD FOR PREPARING CATALYST FOR OLEFIN POLYMERIZATION 한화솔루션 주식회사 2020-06-11 WO claimed
EP-0779295-B1 Metallocenes BASELL POLYOLEFINE GMBH (DE) 2004-10-20 EP claimed
EP-0779306-B1 Process for preparation of cycloolefin copolymers TICONA GMBH (DE) 2003-12-03 EP claimed
US-6114556-A Metallocene compound and its use as catalyst component TARGOR GMBH (DE) 2000-09-05 US claimed
US-6040469-A Metallocene compound TARGOR GMBH (DE) 2000-03-21 US claimed
US-20240239929-A1 Biphasic Polymerization Processes EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-07-18 US disclosed
EP-4347670-A1 BIPHASIC POLYMERIZATION PROCESSES ExxonMobil Chemical Patents Inc. (US) 2024-04-10 EP disclosed
WO-2024059737-A2 CATALYST SYSTEMS AND PROCESSES FOR CYCLIC POLY ALPHA-OLEFINS ExxonMobil Technology and Engineering Company (US) 2024-03-21 WO disclosed
US-20240018278-A1 Improved Process to Prepare Catalyst from In-Situ Formed Alumoxane EXXONMOBIL TECH AND ENGINEERING COMPANY CHEM (US) 2024-01-18 US disclosed
US-20240010660-A1 Toluene Free Supported Methylalumoxane Precursor EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-11 US disclosed
EP-0707016-A1 Catalyst component for producing polyolefin, catalyst for producing polyolefin comprising the catalyst component, and process for producing polyolefin in the presence of the catalyst JAPAN POLYOLEFINS CO., LTD. (JP) 1996-04-17 EP disclosed
EP-0687682-A1 Transition metal compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-20 EP disclosed
EP-0661308-A2 Cyclo-olefin copolymers and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed
EP-0661310-A2 Cyclo-olefincopolymers and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed
EP-0654476-A1 Metallocenes, their preparation and use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010660-A1 Toluene Free Supported Methylalumoxane Precursor KDM7A, MAOA, KDM2A ALDH1A1 529/4885CYP2A6 456/4885HSD17B10 1923/4885
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN ALDH1A1 2135/4885CYP2A6 1527/4885HSD17B10 4150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.