Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816534 | 0.78 | DNMT1 (0.44) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL714429 | 0.78 | CYP2A6 (0.42) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL6545899 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL3783382 | 0.77 | CES1 (0.44) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL145793 | 0.75 | ALDH1A1 (0.44) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL4464838 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL816043 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| SCHEMBL815008 | 0.74 | ALDH1A1 (0.55) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL30932938 | 0.73 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 | |
| Phenanthrene SCHEMBL7643 | 0.73 | CYP2A6 (1.00) | ALDH1A1CYP2A6HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071591-B1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY SCIENCE TECH & RES (SG) | 2021-05-05 | — | — | EP | claimed |
| US-10787483-B2 | Antimicrobial peptidomimetics | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-09-29 | — | — | US | claimed |
| US-20180354989-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-12-13 | — | — | US | claimed |
| US-10053490-B2 | Antimicrobial peptidomimetics | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-08-21 | — | — | US | claimed |
| US-20160333048-A1 | Antimicrobial Peptidomimetics | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-11-17 | — | — | US | claimed |
| EP-3071591-A2 | ANTIMICROBIAL PEPTIDOMIMETICS | Agency For Science, Technology And Research (SG) | 2016-09-28 | — | — | EP | claimed |
| WO-2015112093-A2 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-30 | — | — | WO | claimed |
| WO-2022186098-A1 | STABLE NOVEL AROMATIC BORONIC ACID ESTER | 国立大学法人大阪大学 | 2022-09-09 | — | — | WO | disclosed |
| EP-3071591-B1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY SCIENCE TECH & RES (SG) | 2021-05-05 | — | — | EP | disclosed |
| WO-2020130119-A1 | WNT SIGNALING PATHWAY INHIBITOR | 学校法人京都薬科大学 | 2020-06-25 | — | — | WO | disclosed |
| EP-3287440-B1 | PYRROLIDINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-10053490-B2 | Antimicrobial peptidomimetics | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-08-21 | — | — | US | disclosed |
| US-10040760-B2 | Pyrrolidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-08-07 | — | — | US | disclosed |
| CN-1872857-A | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORP (KR) | 2006-12-06 | — | — | CN | disclosed |
| US-20060084655-A1 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2006-04-20 | — | — | US | disclosed |
| US-20050256096-A1 | C-25 carbamate rifamycin derivatives with activity against drug-resistant microbes | CUMBRE INC. (US) | 2005-11-17 | — | — | US | disclosed |
| CN-1585770-A | Reverse turn mimetics and methods relating thereto | CHOONGWAE PHARMA CORP (KR) | 2005-02-23 | — | — | CN | disclosed |
| US-5616605-A | Peptide derivatives of collagenase inhibitor | RESEARCH CORPORATION TECH., INC. (US) | 1997-04-01 | — | — | US | disclosed |
| US-5387610-A | Treating rheumatoid arthritis, corneal ulceration | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1992022523-A2 | PEPTIDE DERIVATIVES OF COLLAGENASE INHIBITOR | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160333048-A1 | Antimicrobial Peptidomimetics | MLX, MLEC, MRPL21 | ALDH1A1 4340/4885CYP2A6 4086/4885HSD17B10 4771/4885 |
| US-20060084655-A1 | Reverse-turn mimetics and method relating thereto | WNT1, APC, WNT3 | ALDH1A1 4305/4885CYP2A6 4151/4885HSD17B10 3896/4885 |
| US-20050256096-A1 | C-25 carbamate rifamycin derivatives with activity against drug-resistant microbes | CHCHD6, NAT10, RPS25 | ALDH1A1 2070/4885CYP2A6 1017/4885HSD17B10 681/4885 |
| US-10053490-B2 | Antimicrobial peptidomimetics | MLX, MLEC, MRPL21 | ALDH1A1 4340/4885CYP2A6 4086/4885HSD17B10 4771/4885 |
| US-10787483-B2 | Antimicrobial peptidomimetics | MLX, MLEC, MRPL21 | ALDH1A1 4340/4885CYP2A6 4086/4885HSD17B10 4771/4885 |
| US-20180354989-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | MLX, MLEC, MRPL21 | ALDH1A1 4340/4885CYP2A6 4086/4885HSD17B10 4771/4885 |
| US-10040760-B2 | Pyrrolidine compound | CAT, POLI, PPOX | ALDH1A1 783/4885CYP2A6 3123/4885HSD17B10 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.