SCHEMBL2601923

SCHEMBL2601923

CNc1ccc(OCc2ccc3c(c2)C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.52
NPC1 O15118 5/20 0.50
RAB9A P51151 5/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
ALDH1A1 P00352 5/20 0.50
MAPT P10636 5/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
AR P10275 5/20 0.46
HPGD P15428 2/20 0.46
MCHR1 Q99705 1/20 0.46
GSTP1 P09211 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MAOA P21397 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
MAOB P27338 1/20 0.43
CYP1A2 P05177 1/20 0.43
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2601922 0.84 ELANE (0.54) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL2601924 0.84 MAPT (0.68) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL2601920 0.84 NPC1 (0.56) APPNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL28441355 0.82 MAPT (0.56) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL2601925 0.82 MRGPRX4 (0.54) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL2601921 0.81 MAOB (0.56) APPNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2601928 0.78 ALOX5 (0.58) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL665518 0.75 APP (0.69) APPNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL6764114 0.75 RAB9A (0.62) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
Hydrochloric Acid SCHEMBL17890756 0.74 APP (0.67) APPNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956519-B2 Device for detecting an analyte SENOVA SYSTEMS, INC. (US) 2015-02-17 US disclosed
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE SENOVA SYSTEMS, INC. (US) 2012-04-19 US disclosed
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE SENOVA SYSTEMS, INC. (US) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120090995-A1 DEVICE FOR DETECTING AN ANALYTE GPX4, GPX1, AOX1 APP 1409/4885NPC1 4852/4885RAB9A 3669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.