SCHEMBL260225

SCHEMBL260225

F[B-](F)(F)F.N#[N+]c1ccccc1C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
IDO1 P14902 2/20 0.33
AR P10275 1/20 0.32
KIF11 P52732 2/20 0.32
HSD11B1 P28845 2/20 0.32
NFKB1 P19838 1/20 0.32
FABP4 P15090 1/20 0.31
TSHR P16473 1/20 0.31
HTR2C P28335 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261312 0.94 ALDH1A1 (0.39) LMNAGAAALDH1A1POLBTDP1
Hydrochloric Acid SCHEMBL9659775 0.91 ALDH1A1 (0.42) LMNAGAAALDH1A1POLBTDP1
Fluoride Ion SCHEMBL11774111 0.91 ALDH1A1 (0.38) LMNAGAAALDH1A1POLBTDP1
Hydrochloric Acid SCHEMBL18936435 0.91 ALDH1A1 (0.38) LMNAGAAALDH1A1POLBTDP1
SCHEMBL9814307 0.84 ALDH1A1 (0.37) LMNAGAAALDH1A1POLBTDP1
SCHEMBL5573854 0.82 ALDH1A1 (0.39) ALDH1A1TDP1KIF11TSHR
SCHEMBL11526486 0.81 TAS2R14 (0.38) ARHSD11B1
SCHEMBL2380334 0.77 LMNA (0.46) LMNAGAAALDH1A1POLBTDP1
SCHEMBL17937935 0.73 MEN1 (0.33) POLBMEN1KMT2A
SCHEMBL6812746 0.73 KDM1A (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3080852-A1 CHEMICALLY MODIFIED REDUCED GRAPHENE OXIDE AS A SEPARATOR MATERIAL IN SULFUR-CONTAINING BATTERIES Kemijski Institut (SI) 2016-10-19 EP disclosed
US-8133549-B2 Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2012-03-13 US disclosed
US-20090301862-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMEDICS (FR) 2009-12-10 US disclosed
EP-0160239-B1 TEST PIECE FOR DETECTING BILIRUBIN TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1991-08-14 EP disclosed
EP-0160239-A2 Test piece for detecting bilirubin TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1985-11-06 EP disclosed