Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620356 | 0.87 | RARG (0.46) | ALDH1A1HSD17B10RARGPARP1MEN1 | |
| SCHEMBL26026549 | 0.87 | RARG (0.46) | ALDH1A1HSD17B10RARGPARP1MEN1 | |
| SCHEMBL26026709 | 0.82 | RARG (0.46) | ALDH1A1HSD17B10RARGGRIN2DGRIN3B | |
| SCHEMBL29620364 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26027125 | 0.81 | RARG (0.39) | ALDH1A1HSD17B10RARGKMT2ATHRA | |
| SCHEMBL27089947 | 0.79 | PARP1 (0.45) | ALDH1A1HSD17B10GPR35ADRA2AADRA2B | |
| SCHEMBL26027642 | 0.77 | TNKS (0.43) | ALDH1A1RARGMEN1KMT2AMAPT | |
| SCHEMBL29620357 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HSD17B10GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26027474 | 0.75 | ALDH1A1 (0.33) | ALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL29620360 | 0.74 | THRA (0.42) | ALDH1A1MEN1KMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154842-A1 | THR BETA ANALOGS AND USES THEREOF | MADRIGAL PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |