Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.62 |
| ▸ | MMP3 | P08254 | 7/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | HRH2 | P25021 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605873 | 0.85 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL30122612 | 0.84 | L3MBTL1 (0.54) | MAPTHTTL3MBTL1 | |
| SCHEMBL1285929 | 0.84 | MMP2 (0.61) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL1285386 | 0.84 | MMP2 (0.61) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL11613357 | 0.84 | MMP2 (0.55) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL16327389 | 0.83 | MAPT (0.51) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL7778508 | 0.82 | HDAC1 (0.64) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL8409925 | 0.82 | HDAC1 (0.64) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL15970987 | 0.81 | MMP2 (0.59) | MMP2MMP3MMP1MMP9MMP13 | |
| SCHEMBL12736277 | 0.80 | ALDH1A1 (0.63) | MMP2MMP3MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158737-B2 | Method for production of polyfunctional compound | NITTO DENKO CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158737-B2 | Method for production of polyfunctional compound | NITTO DENKO CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158736-B2 | Method for production of polyfunctional compound | NITTO DENKO CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158736-B2 | Method for production of polyfunctional compound | NITTO DENKO CORPORATION (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20110098454-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2011-04-28 | — | — | US | disclosed |
| US-20110098454-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2011-04-28 | — | — | US | disclosed |
| US-20110046358-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2011-02-24 | — | — | US | disclosed |
| US-20110046358-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2011-02-24 | — | — | US | disclosed |
| US-7884167-B2 | conducting a Michael addition of a compound (A) having a hydrogen atom of pKa less than or equal to 15 to a (meth)acrylate or a (meth)acrylamide (B), in which at least one of the compounds (A) and (B) has a photoisomerization group; optical recording material, optical waveguide material | NITTO DENKO CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-7884167-B2 | conducting a Michael addition of a compound (A) having a hydrogen atom of pKa less than or equal to 15 to a (meth)acrylate or a (meth)acrylamide (B), in which at least one of the compounds (A) and (B) has a photoisomerization group; optical recording material, optical waveguide material | NITTO DENKO CORPORATION (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20090182107-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090182107-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | NITTO DENKO CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046358-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | ADCY10, ADCY5, ADCY1 | MMP2 4389/4885MMP3 4693/4885MMP1 4219/4885 |
| US-20110098454-A1 | METHOD FOR PRODUCTION OF POLYFUNCTIONAL COMPOUND | ADCY10, ADCY5, ADCY1 | MMP2 4347/4885MMP3 4671/4885MMP1 4209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.