Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929766 | 0.85 | ALOX5 (0.43) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL23046767 | 0.82 | ALOX5 (0.44) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL22857649 | 0.82 | ALOX5 (0.41) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL6372657 | 0.81 | ALOX5 (0.45) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL15747049 | 0.79 | TOP2A (0.44) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL21763093 | 0.79 | ALOX5 (0.42) | ALOX5MEN1KMT2ACYP2C19AHR | |
| SCHEMBL24864802 | 0.79 | ALOX5 (0.42) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL20172763 | 0.78 | SIGMAR1 (0.45) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL20172791 | 0.78 | PGR (0.40) | ALOX5MEN1KMT2ACYP2C19PGR | |
| SCHEMBL23310406 | 0.78 | ALOX5 (0.50) | ALOX5MEN1KMT2ACYP2C19AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151394-A1 | FLUORENE DERIVATIVE AND USE THEREOF | 上海八亿时空先进材料有限公司 | 2023-08-17 | — | — | WO | disclosed |