SCHEMBL6372657

SCHEMBL6372657

c1ccc2c(c1)oc1c(N(c3cccc4c3oc3ccccc34)c3cccc4c3oc3ccccc34)cccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 3/20 0.45
▸ AHR P35869 3/20 0.43
▸ MAOA P21397 3/20 0.42
▸ KDM4E B2RXH2 4/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ MAPT P10636 3/20 0.40
▸ HPGD P15428 3/20 0.40
▸ GLA P06280 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ PGAM1 P18669 1/20 0.40
▸ CASP1 P29466 1/20 0.40
▸ CASP7 P55210 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23056753 0.91 ALOX5 (0.40) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL14295465 0.90 ALOX5 (0.42) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL15178580 0.89 ALOX5 (0.41) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL15306316 0.89 ALOX5 (0.41) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL14295291 0.87 ALOX5 (0.40) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL25603648 0.87 L3MBTL1 (0.41) ALOX5KDM4EALDH1A1MAPTHPGD
SCHEMBL15730662 0.86 ALOX5 (0.39) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL14295278 0.86 ALOX5 (0.44) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL24471773 0.85 ALOX5 (0.42) ALOX5AHRMAOAKDM4EALDH1A1
SCHEMBL24471767 0.85 ALOX5 (0.44) ALOX5AHRMAOAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 — — US disclosed
US-9054319-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 — — US disclosed
US-20140217378-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-07 — — US disclosed
US-20140217378-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-07 — — US disclosed
US-8759819-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-24 — — US disclosed
US-8759819-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2014-06-24 — — US disclosed
US-20140131680-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 — — US disclosed
US-20140131680-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2014-05-15 — — US disclosed
US-8710493-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2014-04-29 — — US disclosed
US-8710493-B2 Organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2014-04-29 — — US disclosed
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2012-08-09 — — US disclosed
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2012-08-09 — — US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 — — US disclosed
US-20120119197-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-05-17 — — US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 — — US disclosed
US-8106391-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 — — US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 — — US disclosed
US-20100283043-A1 ORGANIC EL ELEMENT IDEMITSU LOSAN CO., LTD. 2010-11-11 — — US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 — — US disclosed
US-20100219404-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120199817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FTO, EML4, SLC43A1 ALOX5 4497/4885AHR 1951/4885MAOA 593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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