SCHEMBL26029258

SCHEMBL26029258

CCCc1cc(Cl)cnc1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.34
MYC P01106 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
HSD17B10 Q99714 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
FLT1 P17948 1/20 0.32
FLT4 P35916 1/20 0.32
KDR P35968 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
SREBF2 Q12772 1/20 0.31
PKM P14618 2/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197804 0.85 ALOX5 (0.39) NPC1RAB9AHSD17B10SMN1; SMN2HTT
SCHEMBL10289728 0.83 HPGD (0.37) PLAUMYCALDH1A1NPSR1HSD17B10
SCHEMBL25442362 0.77 PPARG (0.33) ALDH1A1NPSR1
SCHEMBL19966841 0.77 ALDH1A1 (0.30) ALDH1A1NPSR1
SCHEMBL23514357 0.76 KDM4E (0.35) PLAUMYCALDH1A1RAB9AHPGD
SCHEMBL9263935 0.76 KMT2A (0.39) PLAUALDH1A1NPSR1HSD17B10SMN1; SMN2
SCHEMBL6631024 0.74 PLAU (0.33) PLAUSMN1; SMN2LMNAL3MBTL1
SCHEMBL30058522 0.74 PDXK (0.48) PLAUALDH1A1HSD17B10SMN1; SMN2HPGD
SCHEMBL21100757 0.74 GABRA1 (0.36) PLAUSMN1; SMN2LMNA
SCHEMBL10325290 0.74 PDXK (0.48) PLAUALDH1A1HSD17B10SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4230621-A1 SUBSTITUTED N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer AG (DE) 2023-08-23 EP disclosed