Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 4/20 | 0.47 |
| ▸ | GAK | O14976 | 4/20 | 0.47 |
| ▸ | NLK | Q9UBE8 | 3/20 | 0.47 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547469 | 0.82 | CCNC (0.48) | RIPK2GAKNLKCOQ8ACLK4 | |
| SCHEMBL31510479 | 0.82 | CCNC (0.48) | RIPK2GAKNLKCOQ8ACLK4 | |
| SCHEMBL17811239 | 0.80 | RIPK2 (0.48) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL17257647 | 0.80 | SMN1; SMN2 (0.53) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL15043742 | 0.79 | ALDH1A1 (0.47) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL15043734 | 0.79 | RIPK2 (0.47) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL12025111 | 0.79 | NR4A2 (0.56) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL19499073 | 0.76 | RIPK2 (0.45) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL13676601 | 0.76 | GAK (0.45) | RIPK2GAKNLKCOQ8AFGFR2 | |
| SCHEMBL13676600 | 0.76 | RIPK2 (0.45) | RIPK2GAKNLKCOQ8AFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | RIPK2 2876/4885GAK 1750/4885NLK 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.