Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | RELA | Q04206 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26029175 | 0.85 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL5445828 | 0.85 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2472343 | 0.80 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL4329054 | 0.78 | MAPT (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2476277 | 0.78 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL13945803 | 0.78 | CCR1 (0.43) | HSP90AA1HSP90AB1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL3557626 | 0.77 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL6634465 | 0.77 | HSP90AA1 (0.68) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL2227640 | 0.77 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1PDE10AMAPTALDH1A1 | |
| SCHEMBL7443605 | 0.77 | PDE4A (0.61) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242531-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | HSP90AA1 2117/4885HSP90AB1 1909/4885PDE10A 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.