SCHEMBL26032006

SCHEMBL26032006

CCCCCCCCCCCCCCCC(=O)NCCOCCC(=O)NCCOCCC(=O)NCCN(CCNC(=O)CCOCCNC(=O)CCOCCNC(=O)CCCCCCCCCCCCCCC)C(=O)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.50
FAAH O00519 4/20 0.43
LPAR1 Q92633 2/20 0.41
LPAR2 Q9HBW0 2/20 0.41
ENPP2 Q13822 1/20 0.41
GLP1R P43220 8/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
CASP2 P42575 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032010 0.94 DNM1 (0.46) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL26032011 0.94 DNM1 (0.46) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL26032016 0.92 DNM1 (0.40) DNM1FAAHGLP1RCASP2
SCHEMBL23567384 0.82 FAAH (0.51) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL25067300 0.80 FAAH (0.59) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL21787000 0.80 FAAH (0.49) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL20856919 0.79 FAAH (0.65) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL28999762 0.79 FAAH (0.65) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL31683866 0.79 FAAH (0.65) DNM1FAAHLPAR1LPAR2ENPP2
SCHEMBL16028184 0.77 DNM1 (0.70) DNM1FAAHLPAR1CNR1CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 DNM1 695/4885FAAH 4742/4885LPAR1 1841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.