SCHEMBL26032016

SCHEMBL26032016

CCCCCCCCCCCCCCCCOCCOCCOCCOCCNC(=O)CCOCCNC(=O)CCOCCNC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(=O)NCCOCCC(=O)NCCOCCC(=O)NCCOCCOCCOCCOCCCCCCCCCCCCCCCC)C(=O)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.40
CASP2 P42575 1/20 0.38
TLR2 O60603 2/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
GLP1R P43220 8/20 0.38
EPHX2 P34913 1/20 0.37
NAAA Q02083 1/20 0.37
FAAH O00519 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032011 0.95 DNM1 (0.46) DNM1CASP2GLP1RFAAH
SCHEMBL26032010 0.95 DNM1 (0.46) DNM1CASP2GLP1RFAAH
SCHEMBL26032006 0.92 DNM1 (0.50) DNM1CASP2GLP1RFAAH
SCHEMBL26032013 0.80 DRD2 (0.41) ZDHHC20EPHX2
SCHEMBL23567384 0.79 FAAH (0.51) DNM1CASP2GLP1RFAAH
SCHEMBL25836833 0.77 CASP2 (0.65) DNM1CASP2TLR2EPHX2NAAA
SCHEMBL25067300 0.77 FAAH (0.59) DNM1CASP2GLP1REPHX2NAAA
SCHEMBL18588287 0.77 CASP2 (0.55) DNM1CASP2GLP1REPHX2NAAA
SCHEMBL25110301 0.76 GLP1R (0.52) DNM1GLP1REPHX2FAAH
SCHEMBL21787000 0.76 FAAH (0.49) DNM1CASP2GLP1RFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 DNM1 695/4885CASP2 4432/4885TLR2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.