SCHEMBL26032046

SCHEMBL26032046

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)NCCOCCNC(=O)[C@H](CCC(=O)NCCOCCNC(=O)CCCCCCCCCCCCCCC)NC(=O)CCOCCNC(=O)CCN1C(=O)CC(C(C)C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.44
CNR1 P21554 5/20 0.39
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
TRPV1 Q8NER1 1/20 0.38
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032060 0.96 GLP1R (0.47) GLP1RCNR1
SCHEMBL26032052 0.95 GLP1R (0.48) GLP1RCNR1
SCHEMBL26032070 0.91 GLP1R (0.52) GLP1RHPGD
SCHEMBL26032035 0.91 GLP1R (0.52) GLP1RHPGD
SCHEMBL26032037 0.91 GLP1R (0.52) GLP1RHPGD
SCHEMBL26032096 0.86 GLP1R (0.48) GLP1R
SCHEMBL26032226 0.82 HPGD (0.43) GLP1RHPGD
SCHEMBL25836060 0.81 GLP1R (0.39) GLP1RCNR1
SCHEMBL24589077 0.80 GLP1R (0.55) GLP1R
SCHEMBL26972994 0.80 GLP1R (0.46) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885CNR1 4167/4885ALDH1A1 2528/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.