SCHEMBL26032052

SCHEMBL26032052

CCCCCCCC/C=C\CCCCCCCC(=O)NCCOCCNC(=O)CCOCCNC(=O)CC[C@H](NC(=O)CCOCCOCCNC(=O)CCN1C(=O)CC(C(C)C)C1=O)C(=O)NCCOCCC(=O)NCCOCCNC(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.48
LPAR1 Q92633 2/20 0.38
LPAR2 Q9HBW0 2/20 0.38
ENPP2 Q13822 1/20 0.38
CNR1 P21554 4/20 0.36
EPHX2 P34913 2/20 0.36
OPRK1 P41145 1/20 0.36
SLC6A5 Q9Y345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032060 0.99 GLP1R (0.47) GLP1RLPAR1LPAR2ENPP2CNR1
SCHEMBL26032070 0.95 GLP1R (0.52) GLP1RLPAR1OPRK1
SCHEMBL26032037 0.95 GLP1R (0.52) GLP1RLPAR1OPRK1
SCHEMBL26032035 0.95 GLP1R (0.52) GLP1RLPAR1OPRK1
SCHEMBL26032046 0.95 GLP1R (0.44) GLP1RCNR1
SCHEMBL26032096 0.90 GLP1R (0.48) GLP1ROPRK1
SCHEMBL26032226 0.87 HPGD (0.43) GLP1RLPAR1LPAR2ENPP2
SCHEMBL24589077 0.85 GLP1R (0.55) GLP1ROPRK1
SCHEMBL26972994 0.84 GLP1R (0.46) GLP1REPHX2OPRK1
SCHEMBL24589064 0.82 GLP1R (0.46) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885LPAR1 1841/4885LPAR2 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.