Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603391 | 0.85 | GSK3B (0.57) | MAPTL3MBTL1MMP1GAATHRA | |
| SCHEMBL4275826 | 0.84 | HDAC1 (0.56) | MAPTL3MBTL1GAAHTTPDE3B | |
| SCHEMBL28698021 | 0.84 | GSK3B (0.55) | MAPTL3MBTL1MMP1GAATHRA | |
| SCHEMBL28693965 | 0.84 | GSK3B (0.55) | MAPTL3MBTL1MMP1GAATHRA | |
| SCHEMBL28685533 | 0.84 | GSK3B (0.55) | MAPTL3MBTL1MMP1GAATHRA | |
| SCHEMBL4211416 | 0.83 | TSHR (0.64) | L3MBTL1HTTTP53TSHR | |
| SCHEMBL5187570 | 0.83 | MAPT (0.72) | MAPTL3MBTL1GAANPC1PPARA | |
| SCHEMBL2603390 | 0.83 | L3MBTL1 (0.74) | MAPTL3MBTL1GAAPPARAHTT | |
| SCHEMBL10106958 | 0.83 | MAPT (0.54) | MAPTL3MBTL1MMP1GAATHRA | |
| SCHEMBL9329263 | 0.82 | TSHR (0.67) | GAAHTTTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-9644099-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160355682-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-12-08 | — | — | US | disclosed |
| US-20150050685-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2015-02-19 | — | — | US | disclosed |
| US-8822695-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2014-09-02 | — | — | US | disclosed |
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-17 | — | — | US | disclosed |
| US-8415477-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2013-04-09 | — | — | US | disclosed |
| US-8158801-B2 | Violet laser excitable dyes and their method of use | Life Technologies Corporation (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2012-01-05 | — | — | US | disclosed |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130273569-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | MAPT 378/4885L3MBTL1 1880/4885MMP1 2728/4885 |
| US-20070077549-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | MAPT 378/4885L3MBTL1 1880/4885MMP1 2728/4885 |
| US-20120004397-A1 | VIOLET LASER EXCITABLE DYES AND THEIR METHOD OF USE | KLK3, ALDH1A2, SPR | MAPT 378/4885L3MBTL1 1880/4885MMP1 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.