SCHEMBL26037657

SCHEMBL26037657

Cc1c[nH]c(=S)n(CCCS(C)(=O)=O)c1=O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
MPO P05164 7/20 0.34
XDH P47989 4/20 0.34
ALDH1A1 P00352 2/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
SLC9A1 P19634 1/20 0.33
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
QPCT Q16769 3/20 0.32
ADORA2A P29274 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26037651 0.75 CA9 (0.31) L3MBTL1MPOALDH1A1TSHRHTT
SCHEMBL6471986 0.73 SLC9A1 (0.42) ALDH1A1SLC9A1
SCHEMBL26034573 0.71 ALDH1A1 (0.35) L3MBTL1ALDH1A1HTTRXFP1QPCT
SCHEMBL15110502 0.69 SLC9A1 (0.51) SLC9A1QPCTADORA2A
SCHEMBL16581427 0.65 ADORA2A (0.48) L3MBTL1SLC9A1ADORA2A
SCHEMBL3792986 0.64 SLC9A1 (0.47) SLC9A1ADORA2A
SCHEMBL28021077 0.63 ATAD2 (0.34) ALDH1A1SLC9A1
SCHEMBL8656134 0.63 ALDH1A1 (0.47) L3MBTL1XDHALDH1A1HTTHSD17B10
SCHEMBL4657306 0.63 MAPT (0.42) L3MBTL1ALDH1A1TSHRHTTHSD17B10
SCHEMBL8761973 0.60 ALDH1A1 (0.40) ALDH1A1TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230273455-A1 OPTICALLY ACTIVE DEVICES JOHNSON & JOHNSON SURGICAL VISION INC (US) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230273455-A1 OPTICALLY ACTIVE DEVICES PDE6C, PDE6A, PDE6D L3MBTL1 4743/4885MPO 146/4885XDH 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.