Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871051 | 0.74 | LMNA (0.68) | LMNAKMT2AGLAPOLBGAA | |
| SCHEMBL13941828 | 0.74 | LMNA (0.68) | LMNAKMT2AGLAPOLBGAA | |
| SCHEMBL11160942 | 0.68 | KMT2A (0.55) | LMNAKMT2AGLAPOLBGAA | |
| SCHEMBL4689994 | 0.67 | MAP4K4 (0.39) | PDE1B | |
| SCHEMBL6784767 | 0.67 | ADRA1D (0.46) | EHMT2EHMT1ADRA1DADRA1AADRA1B | |
| SCHEMBL6780798 | 0.67 | KDM4E (0.48) | LMNAGLAGAAADRA1DADRA1A | |
| SCHEMBL11046169 | 0.67 | POLB (0.97) | LMNAKMT2AGLAPOLBGAA | |
| SCHEMBL21227155 | 0.66 | DCPS (0.49) | KMT2AGLAGAAMEN1ADRA1A | |
| Hydrochloric Acid SCHEMBL3637603 | 0.66 | POLB (1.00) | LMNAKMT2AGLAPOLBGAA | |
| SCHEMBL3103845 | 0.65 | LMNA (0.61) | LMNAKMT2AGLAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230624-A1 | QUINAZOLINE-2,4-DIAMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER COMPRISING SAME AS ACTIVE INGREDIENT | The Asan Foundation (KR) | 2023-08-23 | — | — | EP | disclosed |