Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064151 | 0.88 | TSHR (0.40) | TSHRACACBTHRB | |
| SCHEMBL26039699 | 0.81 | TSHR (0.38) | TSHR | |
| SCHEMBL26034463 | 0.77 | TSHR (0.43) | TSHRACACBTHRB | |
| SCHEMBL26034705 | 0.76 | THRB (0.34) | TSHRTHRB | |
| SCHEMBL26034460 | 0.72 | TSHR (0.43) | TSHRTHRB | |
| SCHEMBL16130822 | 0.71 | PKM (0.33) | ACACB | |
| SCHEMBL26034700 | 0.71 | HSD17B13 (0.35) | TSHRTHRB | |
| SCHEMBL25368674 | 0.71 | TSHR (0.47) | TSHRTHRB | |
| SCHEMBL26034717 | 0.69 | LPO (0.40) | TSHRTHRB | |
| SCHEMBL26034769 | 0.69 | LPO (0.35) | TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | TSHR 4592/4885ACACB 3275/4885THRB 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.