SCHEMBL2604386

SCHEMBL2604386

CCc1ccc2c(c1)c1cc(CC)ccc1n2C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
HPGD P15428 6/20 0.58
MAPT P10636 5/20 0.58
KDM4E B2RXH2 5/20 0.58
HSD17B10 Q99714 4/20 0.58
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 1/20 0.49
PGR P06401 1/20 0.49
RORA P35398 1/20 0.49
RORC P51449 1/20 0.49
RORB Q92753 1/20 0.49
PSEN1 P49768 1/20 0.43
PSEN2 P49810 1/20 0.43
APH1B Q8WW43 1/20 0.43
NCSTN Q92542 1/20 0.43
APH1A Q96BI3 1/20 0.43
PSENEN Q9NZ42 1/20 0.43
TSHR P16473 2/20 0.42
HTT P42858 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14984333 0.92 ALDH1A1 (0.51) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL2604392 0.90 MAPT (0.50) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL2604391 0.90 GPR3 (0.59) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL13564046 0.88 MAPT (0.47) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL24797393 0.87 ALDH1A1 (0.47) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL2604389 0.87 MAPT (0.47) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL12083709 0.84 KDM4E (0.56) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL15469003 0.84 RXRA (0.49) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL20411991 0.82 HPGD (0.50) ALDH1A1HPGDMAPTKDM4EHSD17B10
SCHEMBL24797310 0.81 KDM4E (0.45) ALDH1A1HPGDMAPTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10355219-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-16 US disclosed
US-20160343952-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-11-24 US disclosed
US-9419237-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-08-16 US disclosed
US-9123858-B2 Method for manufacturing photoelectric conversion device and a solid-state imaging device having a photoelectric conversion device formed in accordance with the method FUJIFILM CORPORATION (JP) 2015-09-01 US disclosed
US-9123858-B2 Method for manufacturing photoelectric conversion device and a solid-state imaging device having a photoelectric conversion device formed in accordance with the method FUJIFILM CORPORATION (JP) 2015-09-01 US disclosed
US-9102797-B2 Polymers with carbazole structural units MERCK PATENT GMBH (DE) 2015-08-11 US disclosed
US-8994132-B2 Photoelectric conversion element, solid-sate imaging element, imaging apparatus, and method for manufacturing photoelectric conversion element FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
US-8994132-B2 Photoelectric conversion element, solid-sate imaging element, imaging apparatus, and method for manufacturing photoelectric conversion element FUJIFILM CORPORATION (JP) 2015-03-31 US disclosed
US-8969512-B2 Polymers having carbazole structural units MERCK PATENT GMBH (DE) 2015-03-03 US disclosed
US-8860016-B2 Photoelectric conversion device and imaging device FUJIFILM CORPORATION (JP) 2014-10-14 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120098079-A1 PHOTOELECTRIC CONVERSION DEVICE AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2012-04-26 US disclosed
US-20120074513-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-SATE IMAGING ELEMENT, IMAGING APPARATUS, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20120074513-A1 PHOTOELECTRIC CONVERSION ELEMENT, SOLID-SATE IMAGING ELEMENT, IMAGING APPARATUS, AND METHOD FOR MANUFACTURING PHOTOELECTRIC CONVERSION ELEMENT FUJIFILM CORPORATION (JP) 2012-03-29 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20110194000-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-08-11 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100240902-A1 Oxadiazole Derivative, Light-Emitting Element Material, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed
US-20100240902-A1 Oxadiazole Derivative, Light-Emitting Element Material, Light-Emitting Element, Light-Emitting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160343952-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device ARNT, NR2E3, CCNT1 ALDH1A1 42/4885HPGD 2664/4885MAPT 2447/4885
US-20100240902-A1 Oxadiazole Derivative, Light-Emitting Element Material, Light-Emitting Element, Light-Emitting Device, and Electronic Device OXA1L, GRIN1, GRIA1 ALDH1A1 62/4885HPGD 1562/4885MAPT 1071/4885
US-10355219-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device ARNT, NR2E3, CCNT1 ALDH1A1 42/4885HPGD 2664/4885MAPT 2447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.