Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | RXRB | P28702 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26046409 | 0.88 | ALDH1A1 (0.41) | POLBNPSR1THRBIMPDH2GAA | |
| SCHEMBL26046355 | 0.86 | POLB (0.55) | POLBNPSR1FFAR4THRATHRB | |
| SCHEMBL26046489 | 0.81 | HMGCR (0.36) | GAAALDH1A1 | |
| SCHEMBL17616016 | 0.80 | CA2 (0.39) | GAAALDH1A1 | |
| SCHEMBL15354651 | 0.78 | POLB (0.45) | POLBNPSR1PTGER4PTGER3PTGER2 | |
| SCHEMBL23964581 | 0.76 | PTGER4 (0.60) | POLBNPSR1PTGER4PTGER3PTGER2 | |
| SCHEMBL26046358 | 0.76 | POLB (0.50) | POLBNPSR1FFAR4GAAFFAR1 | |
| SCHEMBL15867566 | 0.74 | CA2 (0.43) | GAAALDH1A1 | |
| SCHEMBL26046334 | 0.74 | LMNA (0.47) | POLBNPSR1PTGER4PTGER3PTGER2 | |
| SCHEMBL26046416 | 0.74 | IAPP (0.45) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739354-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2023-08-29 | — | — | US | disclosed |