Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439992 | 0.88 | TSHR (0.42) | MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1218297 | 0.88 | TSHR (0.42) | MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL31731078 | 0.88 | MAPT (0.36) | MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL2990189 | 0.88 | TSHR (0.42) | MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL31731080 | 0.86 | TSHR (0.41) | MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15446640 | 0.84 | TSHR (0.31) | TSHR | |
| SCHEMBL12262571 | 0.84 | TSHR (0.39) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL1470196 | 0.83 | ALDH1A1 (0.39) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL15503226 | 0.82 | MAPK1 (0.34) | TSHR | |
| SCHEMBL15081540 | 0.82 | TDP1 (0.40) | MAPTTSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186930-A1 | USE OF ADDITIVES TO FINE-TUNE THE COMPOSITION OF CARBONATE UNITS IN A POLYMER FORMED BY COPOLYMERIZATION OF CO2 WITH EPOXIDE: APPLICATION TO THE SYNTHESIS OF POLYCARBONATE-BASED BLOCK COPOLYMERS AND OF TELECHELICS | GNANOU, YVES (FR) | 2018-07-05 | — | — | US | disclosed |
| US-9994760-B2 | Polycarbonate block copolymers | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-06-12 | — | — | US | disclosed |
| US-20180079765-A1 | Double Metal Cyanide Catalyst and Epoxide/Carbon Dioxide Copolymer Prepared Using the Same | SK GLOBAL CHEMICAL CO., LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180051134-A1 | COPOLYMERIZATION OF CARBON DIOXIDE AND CYCLIC MONOMERS TO FORM POLYCARBONATES | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2018-02-22 | — | — | US | disclosed |
| US-20170198203-A1 | POLYCARBONATE BLOCK COPOLYMERS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-07-13 | — | — | US | disclosed |
| US-9683077-B2 | Copolymerization of propylene oxide and carbon dioxide without production of propylene carbonate | CORNELL RESEARCH FOUNDATION, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20150307658-A1 | COPOLYMERIZATION OF PROPYLENE OXIDE AND CARBON DIOXIDE WITHOUT PRODUCTION OF PROPYLENE CARBONATE | NATIONAL SCIENCE FOUNDATION | 2015-10-29 | — | — | US | disclosed |
| US-9102800-B2 | Polycarbonate block copolymers | NOVOMER, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-9062155-B2 | Organometallic catalyst and preparation thereof | UNIVERSITY OF SYDNEY (AU) | 2015-06-23 | — | — | US | disclosed |
| US-8785591-B2 | Polycarbonate block copolymers | NOVOMER, INC. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8748555-B2 | Structurally precise poly(propylene carbonate) compositions | NOVOMER, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20140072806-A1 | POLYMER COMPOSITIONS AND METHODS | NOVOMER, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-20140031453-A1 | POLYCARBONATE BLOCK COPOLYMERS | NOVOMER, INC. (US) | 2014-01-30 | — | — | US | disclosed |
| US-8507708-B2 | Organometallic catalyst and preparation thereof | THE UNIVERSITY OF SYDNEY (AU) | 2013-08-13 | — | — | US | disclosed |
| US-20130165623-A1 | COPOLYMERIZATION OF PROPYLENE OXIDE AND CARBON DIOXIDE AND HOMOPOLYMERIZATION OF PROPYLENE OXIDE | Comell Research Foundation, Inc. (US) | 2013-06-27 | — | — | US | disclosed |
| US-20120156410-A1 | STRUCTURALLY PRECISE POLY(PROPYLENE CARBONATE) COMPOSITIONS | NOVOMER, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120093706-A1 | COPOLYMERIZATION OF PROPYLENE OXIDE AND CARBON DIOXIDE AND HOMOPOLYMERIZATION OF PROPYLENE OXIDE | NATIONAL SCIENCE FOUNDATION | 2012-04-19 | — | — | US | disclosed |
| US-8093351-B2 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide | CORNELL RESEARCH FOUNDATION, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20110319645-A1 | ORGANOMETALLIC CATALYST AND PREPARATION THEREOF | UNIVERSITY OF SYDNEY (AU) | 2011-12-29 | — | — | US | disclosed |
| US-20080051554-A1 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319645-A1 | ORGANOMETALLIC CATALYST AND PREPARATION THEREOF | CA2, CA1, CA3 | MAPT 3303/4885TSHR 4595/4885ALDH1A1 2284/4885 |
| US-20180079765-A1 | Double Metal Cyanide Catalyst and Epoxide/Carbon Dioxide Copolymer Prepared Using the Same | RFC2, ERCC1, AOC1 | MAPT 3389/4885TSHR 4803/4885ALDH1A1 4431/4885 |
| US-20080051554-A1 | Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide | SCO2, COX14, KCNN4 | MAPT 3884/4885TSHR 4009/4885ALDH1A1 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.