Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20205764 | 0.81 | FPR2 (0.46) | SORT1CNR1CNR2GRM5 | |
| SCHEMBL20147938 | 0.78 | ALDH1A1 (0.53) | — | |
| SCHEMBL21652031 | 0.77 | POLB (0.50) | — | |
| SCHEMBL20158750 | 0.75 | ALDH1A1 (0.49) | KMT2A | |
| SCHEMBL20147637 | 0.73 | RET (0.41) | CNR2KMT2ATLR9TLR8TLR7 | |
| SCHEMBL26050282 | 0.72 | PARP1 (0.42) | LIMK2ACKR3 | |
| SCHEMBL20158641 | 0.71 | CETP (0.45) | MEN1KMT2AHDAC4 | |
| SCHEMBL7322864 | 0.70 | SMARCA2 (0.46) | SMARCA2SMARCA4SORT1LIMK2MEN1 | |
| SCHEMBL16252564 | 0.70 | SMARCA2 (0.58) | SMARCA2SMARCA4SORT1PSEN1PSEN2 | |
| SCHEMBL20158642 | 0.69 | OPRM1 (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |