Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147938 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2DRD2ALDH1A1CHRM1CETP | |
| SCHEMBL21652031 | 0.73 | POLB (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL26050255 | 0.72 | SMARCA2 (0.44) | ACKR3LIMK2 | |
| SCHEMBL22857089 | 0.72 | DRD2 (0.49) | DRD2ALDH1A1CETP | |
| SCHEMBL20158642 | 0.71 | OPRM1 (0.46) | PARP1ALDH1A1OPRM1OPRK1CETP | |
| SCHEMBL21214329 | 0.71 | HRH3 (0.53) | SMN1; SMN2ALDH1A1CHRM1OPRM1 | |
| SCHEMBL22857073 | 0.69 | ALDH1A1 (0.50) | SMN1; SMN2DRD2ALDH1A1CETP | |
| SCHEMBL20205764 | 0.68 | FPR2 (0.46) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL346787 | 0.67 | GRIA2 (0.40) | OPRM1OPRK1 | |
| SCHEMBL20158750 | 0.67 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150203-A1 | HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |