SCHEMBL260540

SCHEMBL260540

Cc1ccc(Oc2ccc(CO)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.65
TEAD4 Q15561 1/20 0.52
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPBWR1 P48145 1/20 0.48
MMP13 P45452 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK14 Q16539 2/20 0.46
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
EPHX2 P34913 1/20 0.44
MMP2 P08253 2/20 0.42
MMP3 P08254 1/20 0.42
MMP7 P09237 1/20 0.42
MMP9 P14780 1/20 0.42
MMP14 P50281 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5342317 0.88 LTA4H (0.81) LTA4HALDH1A1TDP1MEN1KMT2A
SCHEMBL3337 0.85
SCHEMBL21114374 0.85 IDO1 (0.52) LTA4HTDP1ACHEAGXTIDO1
Ethylene Glycol SCHEMBL27592942 0.83 TEAD4 (0.58) LTA4HTEAD4ALDH1A1POLBMAPT
SCHEMBL806368 0.83 LTA4H (0.47) LTA4HALDH1A1MAPTNPBWR1ACHE
SCHEMBL586153 0.83 IDO1 (0.50) LTA4HALDH1A1POLBMAPTTDP1
SCHEMBL586331 0.83 IDO1 (0.50) LTA4HALDH1A1POLBMAPTTDP1
Ammonia Solution, Strong SCHEMBL28235889 0.83 IDO1 (0.50) LTA4HALDH1A1MAPTTDP1ACHE
SCHEMBL585056 0.83 IDO1 (0.50) LTA4HALDH1A1POLBMAPTTDP1
Methane SCHEMBL27627149 0.83 IDO1 (0.50) LTA4HALDH1A1POLBMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346549-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-11-13 US disclosed
US-20250084023-A2 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2025-03-13 US disclosed
US-20240140895-A1 NOVEL AROMATIC MOLECULES Xeniopro GmbH (DE) 2024-05-02 US disclosed
EP-3326715-B1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE CE PHARM CO LTD (CN) 2021-09-15 EP disclosed
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-07-26 US disclosed
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2018-07-26 US disclosed
EP-3326715-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) 2018-05-30 EP disclosed
EP-3088391-B1 METHOD FOR PRODUCING BENZYL ESTER 2-AMINONICOTINATE DERIVATIVE AGRO-KANESHO CO LTD (JP) 2017-11-29 EP disclosed
US-9695124-B2 Method of producing 2-aminonicotinic acid benzyl ester derivatives AGRO-KANESHO CO., LTD. (JP) 2017-07-04 US disclosed
WO-2017012379-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE 中国科学院上海有机化学研究所 2017-01-26 WO disclosed
US-20160318868-A1 METHOD OF PRODUCING 2-AMINONICOTINIC ACID BENZYL ESTER DERIVATIVES AGRO-KANESHO CO., LTD. (JP) 2016-11-03 US disclosed
EP-3088391-A1 METHOD FOR PRODUCING BENZYL ESTER 2-AMINONICOTINATE DERIVATIVE Agro-Kanesho Co., Ltd. (JP) 2016-11-02 EP disclosed
US-8067440-B2 Phosphonium salts derivatives and uses thereof VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2011-11-29 US disclosed
US-20110092683-A1 PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2011-04-21 US disclosed
US-7880037-B2 Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2011-02-01 US disclosed
US-4692397-A SUBSTRATE COATED WITH A DIAZONIUM SALT; COLORANT AND A POLYVINYL ACETAL RESIN; LITHOGRAPHIC PRINTING PLATES AMERICAN HOECHST CORPORATION (US) 1987-09-08 US disclosed
EP-0126875-B1 LIGHT-SENSITIVE POLYCONDENSATION PRODUCT WITH DIAZONIUM GROUPS, PROCESS FOR THE PREPARATION THEREOF AND LIGHT-SENSITIVE REGISTRATION MATERIAL WHICH CONTAINS THIS POLYCONDENSATION PRODUCT HOECHST AKTIENGESELLSCHAFT (DE) 1987-05-27 EP disclosed
US-4661432-A Light-sensitive, diazonium group-containing polycondensation product, process for its production, and light-sensitive recording material containing this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-28 US disclosed
EP-0126875-A1 Light-sensitive polycondensation product with diazonium groups, process for the preparation thereof and light-sensitive registration material which contains this polycondensation product HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318868-A1 METHOD OF PRODUCING 2-AMINONICOTINIC ACID BENZYL ESTER DERIVATIVES AADAT, SLC1A5, ABAT LTA4H 2763/4885TEAD4 977/4885ALDH1A1 931/4885
US-20110092683-A1 PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF PI4K2A, PIP4K2A, PI4K2B LTA4H 3488/4885TEAD4 3827/4885ALDH1A1 3468/4885
US-20250084023-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LTA4H 3460/4885TEAD4 512/4885ALDH1A1 810/4885
US-20180207628-A1 OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE AOC2, AOC1, AOC3 LTA4H 3436/4885TEAD4 3362/4885ALDH1A1 213/4885
US-20250346549-A2 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LTA4H 3460/4885TEAD4 512/4885ALDH1A1 810/4885
US-20240140895-A1 NOVEL AROMATIC MOLECULES AHR, TYR, MUSK LTA4H 3460/4885TEAD4 512/4885ALDH1A1 810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.