SCHEMBL26056808

SCHEMBL26056808

Cc1c(I)cc(CO)cc1I

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.42
MAPT P10636 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CASP6 P55212 1/20 0.32
TTR P02766 1/20 0.32
TSHR P16473 1/20 0.32
SHBG P04278 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773696 0.81 TTR (0.52) ACHEMAPTKDM4ECASP6TTR
SCHEMBL14259879 0.81 HSD17B10 (0.40) MAPTTSHRHSD17B10
SCHEMBL26262146 0.78 SHBG (0.50) ACHEKDM4ECASP6TTRSHBG
SCHEMBL25368629 0.78 ACHE (0.46) ACHEMAPTKDM4ECASP6TSHR
SCHEMBL13209835 0.76
SCHEMBL13819754 0.76 PTGS2 (0.36)
SCHEMBL2208303 0.73 S1PR1 (0.41) ACHETTRTSHRSHBGCYP4F2
SCHEMBL28223321 0.73 MAPT (0.50) ACHEMAPTTTRTSHRHSD17B10
SCHEMBL31689465 0.73 S1PR1 (0.41) ACHETTRTSHRSHBGCYP4F2
SCHEMBL95656 0.72 ACHE (0.46) ACHEMAPTKDM4ECASP6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230244143-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND COMPOUND JSR CORPORATION (JP) 2023-08-03 US disclosed
US-20230244143-A9 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING RESIST PATTERN, AND COMPOUND JSR CORPORATION (JP) 2023-08-03 US disclosed