SCHEMBL8773696

SCHEMBL8773696

OCc1cc(I)c(O)c(I)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.52
ACHE P22303 1/20 0.50
KDM4E B2RXH2 1/20 0.43
CASP6 P55212 1/20 0.43
ALB P02768 1/20 0.42
THRB P10828 2/20 0.40
ITGB3 P05106 1/20 0.40
ITGAV P06756 1/20 0.40
THRA P10827 1/20 0.40
RXRA P19793 1/20 0.40
PPARG P37231 1/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
SIRT5 Q9NXA8 1/20 0.38
CYP2C9 P11712 3/20 0.37
HIF1A Q16665 2/20 0.37
CYP2C19 P33261 1/20 0.37
SHBG P04278 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26262146 0.91 SHBG (0.50) TTRACHEKDM4ECASP6ALB
SCHEMBL9467420 0.83 TRPV1 (0.50) KDM4ELMNARPS6KA3HSD17B10PDE4D
SCHEMBL26056808 0.81 ACHE (0.42) TTRACHEKDM4ECASP6SHBG
SCHEMBL25368629 0.80 ACHE (0.46) ACHEKDM4ECASP6TBXA2RADRB2
SCHEMBL8773681 0.79 TTR (0.48) TTRKDM4EALBTHRBITGB3
SCHEMBL1126255 0.78 TTR (0.52) TTRALBTHRBITGB3ITGAV
SCHEMBL6103705 0.76 TTR (0.50) TTRALBTHRBITGB3ITGAV
SCHEMBL28223321 0.75 MAPT (0.50) TTRACHETHRBITGB3ITGAV
SCHEMBL12514479 0.74 TTR (0.48) TTRALBTHRBITGB3ITGAV
SCHEMBL670778 0.72 SHBG (0.58) ACHEKDM4ECASP6LMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680599-A1 PROCESS FOR THE SYNTHESIS OF THE COMPOUND 5,7-DIIODO-1-OXASPIRO[2,5]OCTA-4,7-DIEN-6-ONE Innoverda (FR) 2026-01-21 EP claimed
WO-2024189137-A1 PROCESS FOR THE SYNTHESIS OF THE COMPOUND 5,7-DIIODO-1-OXASPIRO[2,5]OCTA-4,7-DIEN-6-ONE INNOVERDA (FR) 2024-09-19 WO claimed
EP-4211104-B1 PROCESS FOR THE SYNTHESIS OF 3,5-DIIODO-4-HYDROXYBENZYL ALCOHOL INNOVERDA (FR) 2024-07-03 EP claimed
US-11834396-B2 Method for synthesizing 3,5-diiodo-4-hydroxy benzyl alcohol INNOVERDA (FR) 2023-12-05 US claimed
US-20230286890-A1 METHOD FOR SYNTHESIZING 3,5-DIIODO-4-HYDROXY BENZYL ALCOHOL DIVERCHIM CDMO (FR) 2023-09-14 US claimed
EP-4211104-A1 PROCESS FOR THE SYNTHESIS OF 3,5-DIIODO-4-HYDROXYBENZYL ALCOHOL Innoverda (FR) 2023-07-19 EP claimed
WO-2022053418-A1 PROCESS FOR THE SYNTHESIS OF 3,5-DIIODO-4-HYDROXYBENZYL ALCOHOL INNOVERDA (FR) 2022-03-17 WO claimed
CN-122070309-A Composition, resin composition, film-forming composition for lithography, and resist film-forming composition 三菱瓦斯化学株式会社 2026-05-19 CN disclosed
EP-4680599-A1 PROCESS FOR THE SYNTHESIS OF THE COMPOUND 5,7-DIIODO-1-OXASPIRO[2,5]OCTA-4,7-DIEN-6-ONE Innoverda (FR) 2026-01-21 EP disclosed
EP-4680599-A1 PROCESS FOR THE SYNTHESIS OF THE COMPOUND 5,7-DIIODO-1-OXASPIRO[2,5]OCTA-4,7-DIEN-6-ONE Innoverda (FR) 2026-01-21 EP disclosed
US-20250250216-A1 CYCLIC COMPOUND HAVING IODINE ATOM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-08-07 US disclosed
CN-120136704-A Compound, polymer, composition for film formation, pattern formation method, method for forming insulating film, and method for producing compound 三菱瓦斯化学株式会社 2025-06-13 CN disclosed
CN-120136703-A Compound, polymer, composition for film formation, pattern formation method, method for forming insulating film, and method for producing compound 三菱瓦斯化学株式会社 2025-06-13 CN disclosed
WO-2021029396-A1 COMPOUND, (CO)POLYMER, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
WO-2021029396-A1 COMPOUND, (CO)POLYMER, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
WO-2021029395-A1 COMPOUND, POLYMER, COMPOSITION, COMPOSITION FOR FILM FORMATION, PATTERN FORMING METHOD, METHOD FOR FORMING INSULATING FILM, METHOD FOR PRODUCING COMPOUND, IODINE-CONTAINING VINYL POLYMER AND METHOD FOR PRODUCING ACETYLATED DERIVATIVE OF SAME 三菱瓦斯化学株式会社 2021-02-18 WO disclosed
WO-2020137935-A1 COMPOUND, (CO)POLYMER, COMPOSITION, PATTERN FORMING METHOD, AND COMPOUND PRODUCTION METHOD 三菱瓦斯化学株式会社 2020-07-02 WO disclosed
WO-2020137935-A1 COMPOUND, (CO)POLYMER, COMPOSITION, PATTERN FORMING METHOD, AND COMPOUND PRODUCTION METHOD 三菱瓦斯化学株式会社 2020-07-02 WO disclosed
EP-0802798-A1 METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS CHIRON CORPORATION (US) 1997-10-29 EP disclosed
WO-1995022992-A1 METHOD AND COMPOSITIONS FOR INCREASING THE SERUM HALF-LIFE OF PHARMACOLOGICALLY ACTIVE AGENTS CHIRON CORPORATION (US) 1995-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250250216-A1 CYCLIC COMPOUND HAVING IODINE ATOM IGF1R, SSTR1, CCNI TTR 2566/4885ACHE 3558/4885KDM4E 4444/4885
US-20230286890-A1 METHOD FOR SYNTHESIZING 3,5-DIIODO-4-HYDROXY BENZYL ALCOHOL ADH1C, ADH5, ADH1A TTR 2169/4885ACHE 3410/4885KDM4E 369/4885
US-11834396-B2 Method for synthesizing 3,5-diiodo-4-hydroxy benzyl alcohol ADH1C, ADH5, ADH1A TTR 2169/4885ACHE 3410/4885KDM4E 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.