Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 14/20 | 0.49 |
| ▸ | F13A1 | P00488 | 11/20 | 0.49 |
| ▸ | TGM1 | P22735 | 8/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25371714 | 0.88 | GPR119 (0.40) | TGM2F13A1TGM1GPR119IDH1 | |
| SCHEMBL26065734 | 0.85 | TGM2 (0.53) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL26065549 | 0.85 | TGM2 (0.53) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL26065641 | 0.84 | TGM2 (0.46) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL26065669 | 0.78 | TGM2 (0.48) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL26065393 | 0.78 | TGM2 (0.53) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL26065252 | 0.78 | TGM2 (0.53) | TGM2F13A1TGM1GPR119TGM3 | |
| SCHEMBL1075431 | 0.78 | IDH1 (0.46) | GPR119IDH1IDH2 | |
| SCHEMBL26066081 | 0.78 | MAPT (0.43) | — | |
| SCHEMBL30719549 | 0.78 | NAMPT (0.44) | TGM2F13A1TGM1GPR119EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |