Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD2 | P25440 | 2/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065673 | 0.79 | PSEN1 (0.40) | ALDH1A1USP2CYP3A4TSHRNFKB1 | |
| SCHEMBL26065697 | 0.78 | TGM2 (0.49) | KDM4E | |
| Trifluoroacetic Acid SCHEMBL25372185 | 0.77 | TRPV4 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065725 | 0.76 | PSEN1 (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL26065730 | 0.76 | CCR1 (0.36) | ALDH1A1KMT2AALOX5APFEN1KDM4E | |
| SCHEMBL25371610 | 0.74 | DDR1 (0.36) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25371575 | 0.72 | RORC (0.42) | — | |
| SCHEMBL26065566 | 0.71 | MAPT (0.47) | ALDH1A1USP2KMT2ACYP3A4TSHR | |
| SCHEMBL26065736 | 0.70 | ALDH1A1 (0.48) | ALDH1A1USP2KMT2AIDH1BRD4 | |
| SCHEMBL25370604 | 0.70 | ALOX5AP (0.34) | ALOX5APFEN1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |