SCHEMBL26067006

SCHEMBL26067006

NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)NCCCCCNC(c1ccccc1)(c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ TRPV1 Q8NER1 1/20 0.38
▸ CHRNA1 P02708 2/20 0.38
▸ CHRNG P07510 2/20 0.38
▸ CHRNB1 P11230 2/20 0.38
▸ CHRND Q07001 2/20 0.38
▸ TSHR P16473 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ NPY1R P25929 1/20 0.37
▸ GRIA1 P42261 2/20 0.35
▸ NAMPT P43490 1/20 0.35
▸ LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26066952 0.79 ALDH1A1 (0.39) KIF11SMN1; SMN2TSHRRECQL
SCHEMBL7263720 0.74 KIF11 (0.65) KIF11SMN1; SMN2TSHRLMNA
SCHEMBL7268298 0.74 KIF11 (0.65) KIF11SMN1; SMN2TSHRLMNA
SCHEMBL7268289 0.73 KIF11 (0.67) KIF11SMN1; SMN2TSHR
SCHEMBL20017289 0.71 MEN1 (0.41) SMN1; SMN2TSHRRECQLLMNA
SCHEMBL7269694 0.71 KIF11 (0.59) KIF11SMN1; SMN2LMNA
SCHEMBL7262278 0.71 KIF11 (0.59) KIF11SMN1; SMN2LMNA
SCHEMBL18475596 0.70 KIF11 (0.54) KIF11SMN1; SMN2
SCHEMBL3136435 0.69 KIF11 (0.61) KIF11CHRNA1CHRNGCHRNB1CHRND
SCHEMBL20107340 0.69 SMN1; SMN2 (0.56) SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME PINOTBIO, INC. (KR) 2023-08-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270867-A1 CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME SLC46A1, SLC47A1, FOLR1 KIF11 1946/4885SMN1; SMN2 4568/4885TRPV1 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback