SCHEMBL26067575

SCHEMBL26067575

CO[C@H]1C(OP(=O)(S)OC[C@@H]2CC[C@H](n3cnc4c(=O)[nH]c(N)nc43)O2)[C@@H](COP(C)(=O)O)O[C@H]1n1cnc2c(N)ncnc21

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 1/20 0.45
▸ NT5E P21589 1/20 0.45
▸ FUT5 Q11128 1/20 0.43
▸ RNASEL Q05823 4/20 0.43
▸ POLB P06746 1/20 0.43
▸ DTYMK P23919 2/20 0.43
▸ TAS1R3 Q7RTX0 1/20 0.42
▸ TAS1R1 Q7RTX1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26067592 0.89 NT5E (0.58) NT5EFUT5RNASELTAS1R3TAS1R1
SCHEMBL26067602 0.89 NT5E (0.58) NT5EFUT5RNASELTAS1R3TAS1R1
SCHEMBL22352078 0.88 RNASEL (0.52) NT5ERNASEL
SCHEMBL20326954 0.88 STING1 (0.47) STING1NT5E
SCHEMBL20324534 0.88 STING1 (0.47) STING1NT5E
SCHEMBL26067692 0.85 DNPH1 (0.63) NT5ERNASELTAS1R3TAS1R1
SCHEMBL23476786 0.84 STING1 (0.46) STING1
SCHEMBL22268153 0.84 RNASEL (0.55) RNASEL
SCHEMBL22268152 0.84 RNASEL (0.55) RNASEL
SCHEMBL22083745 0.84 F2 (0.47) STING1FUT5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS Nanjing GeneLeap Biotechnology Co., Ltd. (CN) 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS RNGTT, RNMT, NSUN2 STING1 761/4885NT5E 338/4885FUT5 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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