SCHEMBL26067720

SCHEMBL26067720

COCCOC1[C@@H](COP(=O)(O)O)O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H]1O

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NT5E P21589 1/20 0.65
IMPDH2 P12268 7/20 0.65
IMPDH1 P20839 2/20 0.65
TAS1R3 Q7RTX0 2/20 0.61
TAS1R1 Q7RTX1 2/20 0.61
TGM2 P21980 1/20 0.61
KRAS P01116 7/20 0.57
FUT5 Q11128 1/20 0.57
HINT1 P49773 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26067683 0.93 TAS1R3 (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL18007485 0.93 TAS1R3 (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL9976681 0.92 NT5E (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL5828417 0.92 NT5E (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL10067882 0.92 NT5E (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL13638722 0.92 NT5E (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL10037916 0.92 NT5E (0.68) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL29092996 0.91 NT5E (0.66) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL25408278 0.90 HINT1 (0.58) NT5EIMPDH2IMPDH1TAS1R3TAS1R1
SCHEMBL26067719 0.90 HINT1 (0.58) NT5EIMPDH2IMPDH1TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS Nanjing GeneLeap Biotechnology Co., Ltd. (CN) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250127-A1 MODIFIED mRNA 5'-CAP ANALOGS RNGTT, RNMT, NSUN2 NT5E 338/4885IMPDH2 860/4885IMPDH1 742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.