Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | MBOAT4 | Q96T53 | 4/20 | 0.36 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006413 | 0.86 | SYK (0.36) | SYKMBOAT4SLC22A12NR1H2EGFR | |
| SCHEMBL26071061 | 0.78 | ADORA2A (0.38) | IGF1RNR1H2EGFRNR1H3 | |
| SCHEMBL26071018 | 0.77 | NOTUM (0.38) | IGF1RSLC22A12 | |
| SCHEMBL26071063 | 0.76 | PPARD (0.52) | — | |
| SCHEMBL26071072 | 0.75 | SLC22A12 (0.40) | IGF1RSLC22A12NR1H2 | |
| SCHEMBL26071083 | 0.74 | SLC22A12 (0.38) | IGF1RSLC22A12HSD17B10JAK2JAK3 | |
| SCHEMBL26071067 | 0.73 | PTGER4 (0.40) | IGF1RSLC22A12HSD17B10JAK2JAK3 | |
| SCHEMBL26071043 | 0.73 | CHEK1 (0.43) | IGF1RSLC22A12 | |
| SCHEMBL26071092 | 0.72 | IGF1R (0.39) | IGF1RSLC22A12JAK2JAK3EGFR | |
| SCHEMBL26071047 | 0.72 | ALOX5 (0.35) | IGF1RSLC22A12EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |