SCHEMBL26077196

SCHEMBL26077196

Fc1ccc2c(c1)COC2(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
PDE3A Q14432 1/20 0.37
SLC6A4 P31645 4/20 0.35
KMT2A Q03164 1/20 0.33
SLC6A2 P23975 2/20 0.33
HTR2C P28335 2/20 0.33
ADRA1A P35348 2/20 0.33
HRH1 P35367 2/20 0.33
OPRM1 P35372 2/20 0.33
DRD3 P35462 2/20 0.33
HTR2B P41595 2/20 0.33
KCNH2 Q12809 2/20 0.33
NPC1 O15118 1/20 0.33
SLC22A1 O15245 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD1 P21728 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17193999 0.77 PGR (0.44) CA1CA2PDE3ASLC6A4SLC6A2
SCHEMBL30574141 0.73 AVPR1A (0.41) CA1CA2PDE3ASLC6A4SLC6A3
SCHEMBL18469608 0.72 SLC6A4 (0.35) CA1CA2PDE3ASLC6A4SLC6A2
SCHEMBL737193 0.70 DPP4 (0.42) HTR2CHTR2ASIGMAR1
SCHEMBL3400246 0.70 AVPR1A (0.42) CA1CA2PDE3AKCNH2
SCHEMBL24204166 0.69 AVPR1A (0.44) KMT2AACHE
SCHEMBL11827622 0.69 AVPR1A (0.46) SIGMAR1
SCHEMBL30574142 0.69 AVPR1A (0.39) CA1CA2PDE3AKMT2ANPC1
SCHEMBL31009472 0.67 SLC5A2 (0.43) CA1CA2PDE3ASLC5A1SLC5A2
SCHEMBL18474236 0.67 PGR (0.45) CA1CA2PDE3AKMT2ASLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness AGROFRESH INC. (US) 2023-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771089-B2 Large-scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness TAS2R10, FOSB, TMBIM6 CA1 3929/4885CA2 3745/4885PDE3A 2224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.