Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16527886 | 0.88 | PTGS2 (0.56) | CNR2PTGS2CYP3A4PTPN1PTPN11 | |
| SCHEMBL9512031 | 0.84 | PTGS2 (0.52) | CNR2PTGS2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL21564352 | 0.79 | ACHE (0.56) | CNR2CNR1KDM1A | |
| SCHEMBL27655657 | 0.78 | CNR2 (0.54) | CNR2PTGS2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL7634231 | 0.77 | TSHR (0.44) | CNR2PTGS2CYP3A4KDM4EALDH1A1 | |
| SCHEMBL67909 | 0.77 | PTGS2 (0.70) | CNR2PTGS2CYP3A4PTPN1PTPN11 | |
| SCHEMBL3362484 | 0.77 | PTGS2 (0.62) | CNR2PTGS2CYP3A4PTPN1PTPN11 | |
| SCHEMBL26077360 | 0.77 | PTGS2 (0.42) | CNR2PTGS2CYP3A4CNR1 | |
| SCHEMBL21551336 | 0.76 | CD274 (0.42) | CNR2CYP3A4KDM4ECNR1KDM1A | |
| SCHEMBL30931798 | 0.76 | CD274 (0.42) | CNR2CYP3A4KDM4ECNR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | CNR2 4165/4885PTGS2 2107/4885CYP3A4 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.