Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | CNR2 | P34972 | 6/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26028249 | 0.82 | IDO1 (0.39) | PTGS2CYP3A4 | |
| SCHEMBL10924622 | 0.80 | PTGS2 (0.62) | PTGS2CYP3A4CNR1CNR2CBS | |
| SCHEMBL26077232 | 0.77 | CNR2 (0.47) | PTGS2CYP3A4CNR1CNR2 | |
| SCHEMBL21551041 | 0.77 | HTT (0.44) | — | |
| SCHEMBL30931759 | 0.77 | HTT (0.44) | — | |
| SCHEMBL10923054 | 0.76 | PTGS2 (0.57) | PTGS2CYP3A4CBSCALM1 | |
| SCHEMBL21551743 | 0.74 | MEN1 (0.40) | CNR1CNR2 | |
| SCHEMBL21551744 | 0.72 | LMNA (0.41) | — | |
| SCHEMBL21564352 | 0.71 | ACHE (0.56) | CNR1CNR2 | |
| SCHEMBL30931859 | 0.70 | HDAC1 (0.35) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | PTGS2 2107/4885CYP3A4 2923/4885CNR1 3600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.