Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30931812 | 0.87 | PLA2G2A (0.43) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21551592 | 0.87 | PLA2G2A (0.43) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL30931785 | 0.82 | PLA2G2A (0.40) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21551224 | 0.82 | PLA2G2A (0.40) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21349340 | 0.79 | KDM4E (0.51) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21550823 | 0.76 | JMJD6 (0.41) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL30931767 | 0.76 | JMJD6 (0.41) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL26077234 | 0.72 | KMT2A (0.46) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL21551390 | 0.71 | KMO (0.43) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL26077458 | 0.71 | TRPV3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | SMN1; SMN2 2206/4885MAPT 3082/4885NPC1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.