Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26082926 | 0.93 | MAPT (0.35) | MAPTTP53SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL26383282 | 0.76 | — | — | |
| SCHEMBL23419323 | 0.72 | MAPT (0.44) | MAPTTP53SMN1; SMN2KDM4EITGB3 | |
| SCHEMBL25997471 | 0.72 | ITGB3 (0.37) | MAPTTP53ITGB3ITGA2BRAB9A | |
| SCHEMBL25997464 | 0.70 | ITGB3 (0.39) | MAPTTP53SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL23419434 | 0.68 | ITGB3 (0.37) | MAPTTP53ITGB3ITGA2BRAB9A | |
| SCHEMBL25997466 | 0.68 | RAB9A (0.37) | MAPTTP53SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL23453356 | 0.63 | MAPT (0.41) | MAPTTP53SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23366318 | 0.63 | TP53BP1 (0.47) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL23419400 | 0.61 | MAPT (0.42) | MAPTTP53SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230314322-A1 | SYSTEMS AND METHODS OF SEQUENCING POLYNUCLEOTIDES | ILLUMINA, INC. | 2023-10-05 | — | — | US | disclosed |