Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26082652 | 0.93 | MAPT (0.35) | MAPTTHRBSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL23419323 | 0.82 | MAPT (0.44) | MAPTTHRBSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL26050477 | 0.76 | — | — | |
| SCHEMBL26051799 | 0.74 | — | — | |
| SCHEMBL25997471 | 0.72 | ITGB3 (0.37) | MAPTNPC1RAB9AHDAC6TP53 | |
| SCHEMBL23453356 | 0.72 | MAPT (0.41) | MAPTTHRBSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23419400 | 0.71 | MAPT (0.42) | MAPTTHRBSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL23419434 | 0.68 | ITGB3 (0.37) | MAPTNPC1RAB9AHDAC6TP53 | |
| SCHEMBL17445577 | 0.67 | ALDH1A1 (0.60) | MAPTTHRBSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29761153 | 0.67 | ALDH1A1 (0.60) | MAPTTHRBSMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230314322-A1 | SYSTEMS AND METHODS OF SEQUENCING POLYNUCLEOTIDES | ILLUMINA, INC. | 2023-10-05 | — | — | US | disclosed |