Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262125 | 0.82 | TSHR (0.36) | — | |
| SCHEMBL2696387 | 0.76 | CA2 (0.31) | — | |
| SCHEMBL15353486 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL148397 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL4299 | 0.73 | — | — | |
| SCHEMBL11504024 | 0.71 | CA2 (0.31) | — | |
| SCHEMBL6221220 | 0.71 | TSHR (0.37) | — | |
| SCHEMBL1067884 | 0.71 | RAPGEF4 (0.31) | — | |
| SCHEMBL1068722 | 0.71 | ENPP3 (0.30) | ENPP3ENPP1 | |
| Benzene SCHEMBL8015826 | 0.70 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145505-A1 | PYRIMIDINE CARBOXAMIDE COMPOUNDS | ACRIVON THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-11897891-B2 | Tricyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2024-02-13 | — | — | US | claimed |
| WO-2023192801-A1 | SULFONAMIDO DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2021113479-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2021-06-10 | — | — | WO | claimed |
| US-20210171535-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2021-06-10 | — | — | US | claimed |
| EP-3041825-B1 | PROCEDURE FOR THE SYNTHESIS OF N-BENZYL-N-CYCLOPROPYL-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-03-13 | — | — | EP | claimed |
| US-9656965-B2 | Procedure for the synthesis of N-benzyl-N-cyclopropyl-1H-pyrazole-4-carboxamide derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-23 | — | — | US | claimed |
| US-20170114053-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERV (US) | 2017-04-27 | — | — | US | claimed |
| EP-3154966-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2017-04-19 | — | — | EP | claimed |
| EP-3080090-A1 | BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2016-10-19 | — | — | EP | claimed |
| EP-2077997-A1 | PYRIDAZINE DERIVATIVES | Syngeta Participations AG (CH) | 2009-07-15 | — | — | EP | claimed |
| WO-2009080314-A1 | PYRIDAZINE DERIVATIVES USEFUL AS FUNGICIDES AND FOR THE TREATMENT OF CANCER | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-02 | — | — | WO | claimed |
| WO-2008089934-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-07-31 | — | — | WO | claimed |
| WO-2008049585-A1 | PYRIDAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-05-02 | — | — | WO | claimed |
| WO-2008049584-A1 | NOVEL PYRIDAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-05-02 | — | — | WO | claimed |
| US-5883044-A | Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners | ROHM AND HAAS COMPANY (US) | 1999-03-16 | — | — | US | claimed |
| EP-0699390-B1 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | claimed |
| US-5693590-A | PLANT GROWTH REGULATOR | ROHM AND HAAS COMPANY (US) | 1997-12-02 | — | — | US | claimed |
| EP-0699390-A2 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM AND HAAS COMPANY (US) | 1996-03-06 | — | — | EP | claimed |
| US-4125620-A | HYPOTENSIVE | BOEHRINGER INGELHEIM GMBH (DE) | 1978-11-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11897891-B2 | Tricyclic heterocycles as FGFR inhibitors | FGFR3, FGFR1, FGFR2 | ENPP3 1801/4885ENPP1 1460/4885 |
| US-20170114053-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | HAVCR2, AR, AKR7A2 | ENPP3 2525/4885ENPP1 2550/4885 |
| US-20210171535-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | FGFR3, FGFR1, FGFR2 | ENPP3 1801/4885ENPP1 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.