SCHEMBL26088643

SCHEMBL26088643

O=c1[nH]c2ccc(F)cc2n(-c2ccccc2)c1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
OPRL1 P41146 1/20 0.48
DAO P14920 2/20 0.46
KDM4E B2RXH2 3/20 0.46
JAK2 O60674 1/20 0.46
JAK3 P52333 1/20 0.46
PGR P06401 1/20 0.45
GABRP O00591 2/20 0.45
GABRD O14764 2/20 0.45
GABRA1 P14867 2/20 0.45
GABRB1 P18505 2/20 0.45
GABRG2 P18507 2/20 0.45
GABRB3 P28472 2/20 0.45
GABRA5 P31644 2/20 0.45
GABRA3 P34903 2/20 0.45
GABRA2 P47869 2/20 0.45
GABRB2 P47870 2/20 0.45
GABRA4 P48169 2/20 0.45
GABRE P78334 2/20 0.45
GABRA6 Q16445 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30910121 1.00 OPRM1 (0.48) OPRM1OPRL1DAOKDM4EJAK2
SCHEMBL26092144 0.91 OPRM1 (0.50) OPRM1OPRL1DAOKDM4EPGR
SCHEMBL30910120 0.91 OPRM1 (0.50) OPRM1OPRL1DAOKDM4EPGR
SCHEMBL5500479 0.88 JAK2 (0.52) DAOKDM4EJAK2JAK3GABRP
SCHEMBL26089069 0.81 ADORA3 (0.48) OPRM1OPRL1KDM4EGABRPGABRD
SCHEMBL30910123 0.81 ADORA3 (0.48) OPRM1OPRL1KDM4EGABRPGABRD
SCHEMBL30910102 0.80 PDE7A (0.51) OPRM1OPRL1KDM4EPGRADORA3
SCHEMBL3150851 0.80 PDE7A (0.51) OPRM1OPRL1KDM4EPGRADORA3
SCHEMBL30770202 0.74 GRIA1 (0.56) OPRM1OPRL1DAOKDM4EPGR
SCHEMBL8145145 0.74 DAO (0.70) OPRM1OPRL1DAOKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700021-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Sapiensbio Inc. (KR) 2026-02-25 EP disclosed
WO-2025127848-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 사피엔스바이오 2025-06-19 WO disclosed
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME SAPIENSBIO INC. (KR) 2025-01-02 US disclosed
EP-4421070-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME Sapiensbio Inc. (KR) 2024-08-28 EP disclosed
WO-2023239227-A1 NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 사피엔스바이오 2023-12-14 WO disclosed
WO-2023068755-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사 사피엔스바이오 2023-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250002464-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME RHOA, ACTR2, MFAP1 OPRM1 3767/4885OPRL1 2836/4885DAO 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.