SCHEMBL26088865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26091668	0.94	AKR1C3 (0.39)	ALDH1A1AVPR1AMEN1KMT2ATSHR
	SCHEMBL26089204	0.90	CHRNB2 (0.44)	ALDH1A1AVPR1AMEN1KMT2ATSHR
	SCHEMBL26088697	0.89	CHRNB2 (0.46)	ALDH1A1AVPR1AMEN1KMT2ATSHR
	SCHEMBL26088510	0.88	SIGMAR1 (0.44)	ALDH1A1AVPR1AMEN1KMT2ATSHR
	SCHEMBL26089277	0.88	KMT2A (0.43)	ALDH1A1MEN1KMT2ATSHRCYP3A4
	SCHEMBL30379848	0.88	KMT2A (0.43)	ALDH1A1MEN1KMT2ATSHRCYP3A4
	SCHEMBL30379065	0.88	KMT2A (0.44)	ALDH1A1MEN1KMT2ATSHRCYP3A4
	SCHEMBL26090863	0.88	KMT2A (0.44)	ALDH1A1MEN1KMT2ATSHRCYP3A4
	SCHEMBL26088765	0.83	SLC6A2 (0.43)	ALDH1A1AVPR1AMEN1KMT2ATSHR
	SCHEMBL26091655	0.82	SLC6A2 (0.45)	ALDH1A1AVPR1AMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.