Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.77 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.76 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720784 | 0.87 | SPR (1.00) | SPRMAPTALDH1A1HPGDPTGS2 | |
| SCHEMBL1130185 | 0.87 | MTNR1A (0.68) | SPRMTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL31543697 | 0.86 | MTNR1A (1.00) | SPRMTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL1771902 | 0.86 | MTNR1A (1.00) | SPRMTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL28872563 | 0.84 | MTNR1A (0.76) | MTNR1AMTNR1BMAPTSMN1; SMN2POLB | |
| SCHEMBL17211923 | 0.84 | MTNR1A (0.76) | SPRMTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL1771890 | 0.84 | MTNR1A (0.80) | SPRMTNR1AMTNR1BMAPTPOLB | |
| SCHEMBL1129747 | 0.83 | MTNR1A (0.63) | SPRMTNR1AMTNR1BMAPTSMN1; SMN2 | |
| SCHEMBL761706 | 0.82 | MEN1 (0.75) | SPRMTNR1AMAPTPOLBGFER | |
| SCHEMBL12720723 | 0.82 | SPR (0.69) | SPRMTNR1AMTNR1BPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | SPR 588/4885MTNR1A 908/4885MTNR1B 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.