Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | HTR2C | P28335 | 5/20 | 0.48 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.45 |
| ▸ | ICMT | O60725 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609178 | 0.84 | HTR2A (0.47) | HTR2AHTR2CPDE4DPDE4APDE4B | |
| SCHEMBL7291102 | 0.82 | PGR (0.41) | HTR2AHTR2CNR3C1PGRNR3C2 | |
| SCHEMBL2608966 | 0.81 | HTR2C (0.49) | HTR2AHTR2CNR1D1NR3C1PGR | |
| SCHEMBL18926938 | 0.79 | SMN1; SMN2 (0.47) | HTR2AHTR2CNR1D1NR3C1PGR | |
| SCHEMBL25154150 | 0.77 | HTR2C (0.76) | HTR2AHTR2C | |
| SCHEMBL18280717 | 0.76 | HTR2C (0.47) | HTR2AHTR2CNR1D1P2RX3P2RX2 | |
| SCHEMBL13283050 | 0.73 | HTR2C (0.76) | HTR2AHTR2CSLC2A1MAPT | |
| SCHEMBL17563245 | 0.73 | ACACB (0.43) | HTR2AHTR2CMAPT | |
| SCHEMBL5022143 | 0.73 | KDM4E (0.41) | PGRTP53MAPTDAO | |
| SCHEMBL26674354 | 0.71 | NR1D1 (0.47) | HTR2AHTR2CNR1D1ICMTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | HTR2A 4221/4885HTR2C 4182/4885NR1D1 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.