Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19757663 | 1.00 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL19757658 | 1.00 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1CYP3A4 | |
| Dimethylamine SCHEMBL28476469 | 0.94 | CYP3A4 (0.49) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL21030387 | 0.87 | CYP3A4 (0.43) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL21031031 | 0.87 | CYP3A4 (0.43) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL21030364 | 0.87 | CYP3A4 (0.43) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL20604375 | 0.86 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL20604377 | 0.86 | ALOX5 (0.46) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL31556325 | 0.85 | CES2 (0.52) | ALOX5CES2CES1KEAP1CYP3A4 | |
| SCHEMBL13957844 | 0.83 | ALOX5 (0.47) | ALOX5CES2CES1KEAP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096739-B2 | Cellulose acetate film | SK INNOVATION CO., LTD. (KR) | 2015-08-04 | — | — | US | disclosed |
| US-20150053113-A1 | Cellulose Acetate Film | SK INNOVATION CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | HAVCR2, MAVS, GTF3C1 | ALOX5 4514/4885CES2 1730/4885CES1 361/4885 |
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | ALOX5 2385/4885CES2 1026/4885CES1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.