Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | SCN1A | P35498 | 1/20 | 0.65 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.65 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197468 | 1.00 | ADRA1A (0.75) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL7786034 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL34158 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL5172508 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL4258097 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL4258100 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL146222 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL29763696 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL1043727 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A | |
| Methoxamine SCHEMBL5172511 | 0.86 | ADRA1A (1.00) | ADRA1AADRA2ACYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101091-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2E | ADRA1A 2783/4885ADRA2A 3168/4885CYP2D6 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.