SCHEMBL26089974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22074852	0.81	NR1H2 (0.40)	MAPK1NR1H2POLBESR2USP2
	SCHEMBL15933479	0.81	NR1H2 (0.40)	MAPK1NR1H2POLBESR2USP2
	SCHEMBL3133282	0.79	DPP4 (0.46)	MAPK1NR1H2ESR2USP2SMN1; SMN2
	SCHEMBL2654149	0.79	NR1H2 (0.38)	MAPK1NR1H2POLBESR2USP2
	SCHEMBL25431827	0.78	GPR119 (0.43)	NR1H2ESR2USP2SMN1; SMN2MAPT
	SCHEMBL5232729	0.78	DPP4 (0.44)	MAPK1NR1H2ESR2USP2SMN1; SMN2
	SCHEMBL20140942	0.75	CKS1B (0.49)	MAPK1ESR2MAPTALDH1A1CKS1B
	SCHEMBL2527853	0.75	ADORA1 (0.45)	NR1H2POLBSMN1; SMN2MAPTALDH1A1
	SCHEMBL15933697	0.74	GPR119 (0.47)	MAPK1NR1H2POLBESR2CKS1B
	SCHEMBL15933643	0.74	GPR119 (0.45)	MAPK1NR1H2ESR2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.