Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL261965 | 0.85 | ALDH1A1 (0.39) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL261181 | 0.82 | POLB (0.53) | TDP1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL3822964 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL261589 | 0.78 | TDP1 (0.71) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11077941 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20990648 | 0.74 | POLB (0.46) | TDP1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL22315112 | 0.74 | ALDH1A1 (0.53) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL21348853 | 0.74 | KMT2A (0.57) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL19634634 | 0.73 | MAOA (0.56) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL22215822 | 0.73 | TDP1 (0.67) | SMN1; SMN2TDP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097375-B1 | METHOD FOR PURIFYING BISIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-04-24 | — | — | EP | disclosed |
| EP-2089348-B1 | METHOD FOR MAKING POLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2013-02-20 | — | — | EP | disclosed |
| US-8134016-B2 | Method for purifying dianhydrides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-03-13 | — | — | US | disclosed |
| EP-2094691-B1 | METHOD FOR PURIFYING DIANHYDRIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2011-05-25 | — | — | EP | disclosed |
| EP-2097375-A1 | METHOD FOR PURIFYING BISIMIDES | Sabic Innovative Plastics IP B.V. (NL) | 2009-09-09 | — | — | EP | disclosed |
| EP-2094691-A1 | METHOD FOR PURIFYING DIANHYDRIDES | Sabic Innovative Plastics IP B.V. (NL) | 2009-09-02 | — | — | EP | disclosed |
| EP-2089348-A1 | METHOD FOR MAKING POLYETHERIMIDES | Sabic Innovative Plastics IP B.V. (NL) | 2009-08-19 | — | — | EP | disclosed |
| US-20080319210-A1 | METHOD FOR PURIFYING DIANHYDRIDES | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2008-12-25 | — | — | US | disclosed |
| US-7446214-B2 | Method for purifying oxybisphthalic anhydrides | SABIC INNOVATIVE PLASTICS IP B.V. (US) | 2008-11-04 | — | — | US | disclosed |
| US-7411032-B2 | Method for making polyetherimides | SABIC INNOVATIVE PLASTICS IP B.V. (US) | 2008-08-12 | — | — | US | disclosed |
| US-7408070-B2 | Method for purifying bisimides | SABIC INNOVATIVE PLASTICS IP B.V. (US) | 2008-08-05 | — | — | US | disclosed |
| WO-2008063206-A1 | METHOD FOR MAKING POLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063208-A1 | METHOD FOR PURIFYING BISIMIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008063207-A1 | METHOD FOR PURIFYING DIANHYDRIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
| US-20070073063-A1 | Method for purifying bisimides | GENERAL ELECTRIC COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070073035-A1 | Method for making polyetherimides | GENERAL ELECTRIC COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070073066-A1 | Method for purifying dianhydrides | GENERAL ELECTRIC COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073063-A1 | Method for purifying bisimides | FHIT, PBRM1, TNS4 | SMN1; SMN2 1842/4885TDP1 2431/4885KMT2A 363/4885 |
| US-20080319210-A1 | METHOD FOR PURIFYING DIANHYDRIDES | AQP4, TRRAP, GYPA | SMN1; SMN2 2824/4885TDP1 1104/4885KMT2A 266/4885 |
| US-20070073066-A1 | Method for purifying dianhydrides | AQP4, TRRAP, GYPA | SMN1; SMN2 2824/4885TDP1 1104/4885KMT2A 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.