Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17318141 | 0.84 | LMNA (0.50) | ALDH1A1MAPTKDM4EHTTTDP1 | |
| SCHEMBL4848781 | 0.73 | BCHE (0.55) | ALDH1A1MAPTKDM4EKMT2ABCHE | |
| SCHEMBL811061 | 0.73 | ALDH1A1 (0.76) | PKMALDH1A1MAPTKDM4EHTT | |
| SCHEMBL27838448 | 0.72 | CES2 (0.52) | KDM4ETDP1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL16042071 | 0.72 | F2 (0.50) | PKMALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL135563 | 0.71 | F2 (0.53) | PKMALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9738285 | 0.71 | F2 (0.53) | PKMALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL10047332 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL14193468 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4ETDP1KMT2A | |
| SCHEMBL12444212 | 0.71 | ALDH1A1 (0.68) | ALDH1A1MAPTKDM4ETDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070483-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1R, 2S, 2aS) -1, 2, 3, 3, 4, 4-HEXAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) -OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | claimed |
| WO-2023076532-A1 | PROCESSES OF MAKING 3-FLUORO-5-(((1R,2S,2AS)-1,2,3,3,4,4-HEXAFLUORO-2A-HYDROXY-2,2A,3,4-TETRAHYDRO-1H- CYCLOPENTA[CD]INDEN-7-YL)-OXY)-BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023070483-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1R, 2S, 2aS) -1, 2, 3, 3, 4, 4-HEXAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) -OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |