Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099496 | 0.84 | PKM (0.47) | LMNAKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL17137206 | 0.80 | KMT2A (0.51) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27735833 | 0.78 | ALDH1A1 (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17137285 | 0.78 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27922288 | 0.78 | LMNA (0.47) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17137317 | 0.77 | ALDH1A1 (0.49) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL17318146 | 0.75 | HTR6 (0.42) | LMNAKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL18093538 | 0.74 | ALDH1A1 (0.43) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL135563 | 0.72 | F2 (0.53) | LMNAKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9738285 | 0.72 | F2 (0.53) | LMNAKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-08-19 | — | — | US | disclosed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-10-06 | — | — | US | disclosed |
| US-20220000799-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-01-06 | — | — | US | disclosed |
| EP-3892610-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT | The Scripps Research Institute (US) | 2021-10-13 | — | — | EP | disclosed |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-10-12 | — | — | US | disclosed |
| EP-3151817-B1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | SCRIPPS RESEARCH INST (US) | 2021-03-03 | — | — | EP | disclosed |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-24 | — | — | US | disclosed |
| CN-111689929-A | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-09-22 | — | — | CN | disclosed |
| US-10765645-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-08 | — | — | US | disclosed |
| CN-106659700-B | Sulfur fluoride (VI) compound and preparation method thereof | 斯克里普斯研究所 | 2020-07-10 | — | — | CN | disclosed |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-31 | — | — | US | disclosed |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2017-07-13 | — | — | US | disclosed |
| EP-3151817-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | The Scripps Research Institute (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015188120-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196985-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, NAF1, CYP2S1 | LMNA 2051/4885KMT2A 2082/4885MEN1 320/4885 |
| US-10765645-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | HAX1, CYP2F1, CYP4X1 | LMNA 2434/4885KMT2A 2064/4885MEN1 895/4885 |
| US-12390424-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | GRB2, SCTR, OGFR | LMNA 4654/4885KMT2A 3250/4885MEN1 1934/4885 |
| US-20220313624-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | QSOX1, YBX1, SFXN1 | LMNA 3340/4885KMT2A 1800/4885MEN1 1251/4885 |
| US-20220000799-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | PTMS, IGF2R, SCTR | LMNA 4605/4885KMT2A 3438/4885MEN1 728/4885 |
| US-20190029972-A1 | SULFUR(VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | HAX1, CYP2F1, CYP4X1 | LMNA 2434/4885KMT2A 2064/4885MEN1 895/4885 |
| US-20200397719-A1 | SULFUR (VI) FLUORIDE COMPOUNDS AND METHODS FOR THE PREPARATION THEREOF | CYP2F1, CYP2S1, NAF1 | LMNA 2176/4885KMT2A 2325/4885MEN1 423/4885 |
| US-11141385-B2 | Sulfur (VI) fluoride compounds and methods for the preparation thereof | CYP2F1, CYP2S1, NAF1 | LMNA 2176/4885KMT2A 2325/4885MEN1 423/4885 |
| US-10117840-B2 | Sulfur(VI) fluoride compounds and methods for the preparation thereof | CYP2F1, NAF1, CYP2S1 | LMNA 2051/4885KMT2A 2082/4885MEN1 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.